Commentary: Tumefactive Demyelinating Lesions as a First Clinical Event: Clinical, Imaging, and Follow-up Observations

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Commentary: Tumefactive Demyelinating Lesions as a First Clinical Event: Clinical, Imaging, and Follow-up Observations

BACKGROUND Tumefactive demyelinating lesions (TDLs) are associated with a variety of demyelinating diseases in the central nervous system (CNS). However, there are no current guidelines describing how to classify and treat patients with this rare phenotype. Thus, the present study aimed to determine the long-term evolution and disease course of patients initially presenting with TDLs and to des...

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Magnetic Resonance Imaging Characteristics of Tumefactive Demyelinating Lesions

Tumefactive demyelinating lesions (TDLs) are often misdiagnosed as brain tumors. To identify imaging characteristics of TDLs for their proper diagnosis, their differences from malignant gliomas, etc., were investigated based on 3-Tesla magnetic resonance imaging (MRI) and MR spectroscopy data that was obtained from 5 patients diagnosed with TDLs in our hospital. MRI displayed a paraventricular ...

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Proton MR spectroscopy of tumefactive demyelinating lesions.

BACKGROUND AND PURPOSE Tumefactive demyelinating lesions (TDLs) can simulate intracranial neoplasms in clinical presentation and MR imaging appearance, and surgical biopsy is often performed in suspected tumors. Proton MR spectroscopy has been applied in assessing various intracranial diseases and is increasingly used in diagnosis and clinical management. Our purpose was to determine if multivo...

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Case Series: tumefactive demyelinating lesions: a diagnostic challenge.

T umefactive demyelinating lesion (TDL) is defined as a solitary de myelin ating lesion greater than 2 cm. Mass effect and contrast enhancement on neuroimaging make it difficult to distinguish this type of lesion from high-grade gliomas. Multiple sclerosis (MS) accounts for most cases of TDL. Even in patients with established MS, an atypical manifestation of a large lesion can suggest concurren...

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ژورنال

عنوان ژورنال: Frontiers in Neurology

سال: 2016

ISSN: 1664-2295

DOI: 10.3389/fneur.2016.00222